We hypothesize that small 5 nm size positively charged nanoparticles could specifically target bacterial cell wall and adherent fimbriae expression, serving as the next generation antibacterial agent. To tackle growing antibiotic resistance (AR) and hospital-acquired infections (HAIs), novel antimicrobials are warranted that are effective against HAIs and safer for human use. The energy content is a reflection to structure equilibrium and its stability for nature tendency. As expected, the hexagon shape is packed with the lowest surface parameter and very stable in single unit or array form by showing the lowest energy reduction. From the result, it is found that the reduction of surface energy ranged from 10-23 percent from the initial shape. The study was carried out by comparing hexagon with triangle, trapezium, and square. Based on the phenomenon, this study was carried out to investigate the effect of surface tension, energy, and geometry features, which affect the tendency of hexagon formation. There are many regular and irregular shapes available in nature, but the shape formation still leads to hexagon at the end of the Even though each of the unit shapes size may vary, the noticeable elements that built up the array are hexagons.
![honeycomb shape honeycomb shape](https://www.urbanbrush.net/en/wp-content/uploads/edd/2018/11/urbanbrush-20181109142340980714.png)
The array of bubbles and honeycomb is formed by merging and sharing the common wall with the adjacent unit. Nature, for instance, bubble and honeycomb, tend to form a hexagon shape naturally. Keeping the IPoSM framework in mind, teacher educators could elaborate more effective problem-based integrated approaches of science and mathematics in initial teacher education. The IPoSM framework indicators proved to be useful for identifying the level of integration of science and mathematics in PSTs’ work in each phase of the PBL activity.
HONEYCOMB SHAPE FULL
However, full integration with meaningful connections between science and mathematics ideas was achieved by almost all PST at the conclusion of the research problem. In general, results show that PSTs’ integration performance was higher with the second problem than with the first problem. The final participants were 13 PSTs, organized in four working groups.
![honeycomb shape honeycomb shape](https://fairgaze.com/images/UploadedImages/thumbs/0073827_0073827_2.jpg)
A qualitative methodology was used, focused on the application of the framework to the work of PSTs in that PBL activity. This PBL activity was structured as a research problem divided into two integrated problems. The framework is organized in three levels of integration, based on current research, and detailed with specific integration indicators about an exemplary PBL activity, named STEM Bees. It also presents the classification of PSTs’ level of integration in each phase of a problem-based learning (PBL) activity, within the proposed framework, and evidence of their work. This paper presents a framework and a research design proposal to identify preservice teachers’ (PSTs) integration performance of science and mathematics (IPoSM). Integration is an important, albeit difficult, goal of science and mathematics education.